一、 基本信息
阿瓦古丽·达吾提,北京协和医学院药理学医学博士,新疆维吾尔自治区“天池英才”青年博士人才。主要致力于新疆地产民族药活性成分的发现、作用靶点和药理机制研究。目前主持天池英才项目1项。在biomedicine & pharmacotherapy, international journal of molecular science,aging等学科一流或学科重要杂志上发表sci论文6篇。参编著名出版社springer出版的英文论著《aquaporins》。
二、主持科学研究项目
1.自治区“天池英才”青年博士人才项目《维药益心巴迪然吉布亚颗粒对hfpef的治疗作用、关键成分发现与靶点确认》。
三、讲授课程
1. 本科生课程:《药理学》《药理学实验》《药物毒理学》
四、代表性成果
[1]awaguli dawuti, shuchan sun , ranran wang, difei gong, ruiqi liu , dewen konga,tianyi yuan, jian zhou, yang lu , shoubao wang , guanhua du, lianhua fang. salvianolic acid a alleviates heart failure with preserved ejection fraction via regulating tlr/myd88/traf/nf-κb and p38mapk/creb signaling pathways. biomedicine & pharmacotherapy, 2023, 168: 115837.(if= 7.5)
[2]awaguli dawuti, shuchan sun, ranran wang, difei gong, tianyi yuan, li zhang, shiying yang, yang lu, shoubao wang, lianhua fang, guanhua du. systems pharmacology-based strategy to investigate pharmacological mechanisms of total flavonoids in dracocephalum moldavica on chronic heart failure. int j mol sci.2022 jul;23(15):8409.(if= 5.6)
[3]awaguli dawuti, lisha ma, xueyan an, jiawei guan, changdong zhou, linyun he, yue xu, bo han, abudumijiti abulizi. exploring the effect and mechanism of aloin a against cancer cachexia-induced muscle atrophy via network pharmacology, molecular docking, molecular dynamics and experimental validation. aging. 2023 dec 29;15(24):15557-15577. (if=5.2)
[4]shuchan sun, awaguli dawuti, difei gong, ranran wang, tianyi yuan, shoubao wang, cheng xing, yang lu, guanhua du, lianghua fang. puerarin-v improve mitochondrial respiration and cardiac function in a rat model of diabetic cardiomyopathy via inhibiting pyroptosis pathway through p2x7 receptors. int j mol sci. 2022 oct 27; 23(21):13015. (if= 5.6)
[5]difei gong, shuchan sun, ranran wang, awaguli dawuti, dewen kong, ruiqi liu, lida du, shoubao wang, yang lu, tianyi yuan, guanhua du, lianhua fang. salvianolic acid a improve mitochondrial respiration and cardiac function via inhibiting apoptosis pathway through cryab in diabetic cardiomyopathy. biomedicine & pharmacotherapy. 2023 apr: 160:114382. (if=7.5)
[6]difei gong, tianyi yuan, ranran wang, shuchan sun, awaguli dawuti, shoubao wang, guanhua du, lianhua fang. network pharmacology approach and experimental verification of dan-shen decoction in the treatment of ischemic heart disease. pharm biol. 2023 dec;61(1):69-79. (if=3.55)
[7]阿瓦古丽·达吾提,方莲花,杜冠华. 丹酚酸对缺血性心脏病的作用及作用机制研究进展[j].药学学报, 2021, 56(02):368-373. (北大核心)
[8]阿瓦古丽·达吾提,任利文,王冉冉,方莲花,杜冠华. 治疗心力衰竭中药有效成分网络药理学研究[j]. 中药药理与临床, 2020, 36(5):131-136. (北大核心)
[9]阿瓦古丽·达吾提, 刘丹,阿迪拉·迪力夏提,阿布来提·阿布力孜,阿地力江·萨吾提,艾再提·克日木,阿迪力·阿不都热合曼,邬利娅·伊明. 性别及雌激素水平对肾血管性高血压大鼠血管组织ace1-angⅱ-atr轴的影响[j].中国药理学通报, 2019, 35(06):859-863. (北大核心)
五、800cc全讯白菜的联系方式
1. e-mail:awaguli@shzu.edu.cn
2. 通讯地址:新疆维吾尔自治区石河子市,北2路59号,石河子大学医学校区,药学院
3. 邮编:832002